Amelanotic / hypomelanotic melanoma

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Main PageMELANOMAAmelanotic / hypomelanotic melanoma
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 Author(s): Lauren Fried
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Below are dermoscopic features commonly associated with the diagnosis “Amelanotic / hypomelanotic melanoma”.[1] The example images have been approved by a panel of experts as representative of each given feature.

For a more in-depth discussion of associated features, please see the Dermoscopedia page for “Amelanotic / hypomelanotic melanoma”.

Scar-like depigmentation

Area of white that is whiter than surrounding normal skin (true scarring). It should not be confused with hypo- or depigmentation due to simple loss of melanin.[2]

Milky red areas

White shiny lines (crystalline structures)

Short, white, shiny lines that might be parallel or vertical to one another. Only seen with polarized dermoscopy.[3]

Atypical vascular pattern, polymorphous vessels (2+ types of blood vessels, e.g. linear irregular and dotted vessels)

  1. Fried LJ, Tan A, Berry EG, et al. Dermoscopy Proficiency Expectations for US Dermatology Resident Physicians: Results of a Modified Delphi Survey of Pigmented Lesion Experts. JAMA Dermatol. Published online January 06, 2021. doi:10.1001/jamadermatol.2020.5213
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