Squamous cell carcinoma

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Main PageNONMELANOCYTIC LESIONSSquamous cell carcinoma
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 Author(s): Lauren Fried
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Description Below are dermoscopic features commonly associated with the diagnosis “Squamous cell carcinoma”. The example images have been approved by a panel of experts as representative of each given feature.


For a more in-depth discussion of associated features, please see the Dermoscopedia page for “Squamous cell carcinoma”.

Author(s) Lauren Fried
Responsible author N.N.→ send e-mail
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Status by Ralph P. Braun


Below are dermoscopic features commonly associated with the diagnosis “Squamous cell carcinoma”.[1] The example images have been approved by a panel of experts as representative of each given feature.

For a more in-depth discussion of associated features, please see the Dermoscopedia page for “Squamous cell carcinoma”.

Yellow keratin mass / scale crust[edit]

The keratin mass consists of amorphous, yellow-white to light-brown areas without any recognizable structure.[1]

White circles (“keratin pearls”)[edit]

Rosette sign[edit]

White, four-leaf clover-shaped structure; can only be seen with polarized dermoscopy.[2]

Glomerular (coiled) blood vessels[edit]

Glomerular vessels are the dermoscopic manifestations of tortuous, dilated capillaries.[3]

Hairpin vessels, usually with whitish halo[edit]

Hairpin (looped) vessels are characterized by vessels that resemble hairpins, consisting of a U-shape with a sharp bend at one end.[4]

Ulceration / blood spots/ hemorrhage [edit]

Ulceration consists of large, irregularly shaped or roundish areas of dull red or red-brown structureless color.[5]

  1. Fried LJ, Tan A, Berry EG, et al. Dermoscopy Proficiency Expectations for US Dermatology Resident Physicians: Results of a Modified Delphi Survey of Pigmented Lesion Experts. JAMA Dermatol. Published online January 06, 2021. doi:10.1001/jamadermatol.2020.5213